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Oh Dear. E Coli Not From Cucumbers – A Bioweapon?

June 7, 2011


The genetic code reveals the history

When scientists at Germany’s
Robert Koch Institute decoded the genetic makeup of the O104 strain, they
found it to be resistant to all the following classes and combinations of

• penicillins
• tetracycline
• nalidixic acid
• trimethoprim-sulfamethoxazol
• cephalosporins
• amoxicillin / clavulanic acid
• piperacillin-sulbactam
• piperacillin-tazobactam

addition, this O104 strain posses an ability to produce special enzymes that
give it what might be called “bacteria superpowers” known technically as

“Extended-Spectrum Beta-Lactamases (ESBLs) are enzymes that
can be produced by bacteria making them resistant to cephalosporins e.g.
cefuroxime, cefotaxime and ceftazidime – which are the most widely used
antibiotics in many hospitals,” explains the Health Protection Agency in the UK

On top of
that, this O104 strain possesses two genes — TEM-1 and CTX-M-15 — that
“have been making doctors shudder since the 1990s,” reports The Guardian
(…). And why do they make doctors shudder? Because they’re so deadly that many people infected with such
bacteria experience critical organ failureand simply die.

Bioengineering a deadly superbug

So how, exactly, does a bacterial
strain come into existence that’s resistant to over a dozen antibiotics in
eight different drug classes
and features two deadly gene mutations plus
ESBL enzyme capabilities?

There’s really only one way this happens (and
only one way) — you have to expose this strain of e.coli to all eight
classes of antibiotics drugs. Usually this isn’t done at the same time, of
course: You first expose it to penicillin and find the surviving colonies which
are resistant to penicillin. You then take those surviving colonies and expose
them to tetracycline. The surviving colonies are now resistant to both
penicillin and tetracycline. You then expose them to a sulfa drug and collect
the surviving colonies from that, and so on. It is a process of genetic
done in a laboratory with a desired outcome. This is essentially
how some bioweapons are engineered by the U.S. Army in its laboratory
facility in Ft. Detrick, Maryland…”

Learn more:

Or how bioweapons are engineered in any country for that matter.
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